Eosinophilic Esophagitis and Celiac Disease EP069

Your gastrointestinal tract is approximately 30 feet long, and it runs from your mouth all the way to the anus! We know that celiac disease can impact any part of the digestive tract. But there is another disease that wreaks havoc on the GI tract as well, a condition called eosinophilic esophagitis or EoE.

The Gluten Free RN is explaining the fundamentals of eosinophilic esophagitis, from its characteristic inflammation of the esophagus and elevated eosinophils in the blood to the common symptoms of vomiting and upper abdominal pain. She walks us through the treatment for EoE, an elimination diet or steroid therapy.

Nadine speaks to the research exploring a possible connection between eosinophilic esophagitis and celiac disease, citing a paper that found a higher prevalence of EoE in children with celiac disease than the general population as well as the case study of a woman with both celiac disease and elevated eosinophils in her blood. Listen in for the Gluten Free RN’s insight on the best EoE clinics and physicians in the country and learn why further study is needed around EoE and celiac disease!

What’s Discussed:

The fundamentals of eosinophilic esophagitis

Allergic response to dietary antigens
Causes inflammation of esophagus, increased eosinophils in blood

The benefits of unsedated transnasal endoscopy for children with EoE

Monitors esophageal mucosa without sedation
Safer, faster and less costly

Some common symptoms of eosinophilic esophagitis

Vomiting, difficulty swallowing, food stuck in throat
Chest pain, heartburn, upper abdominal pain

The condition of achalasia

Muscles of esophagus don’t work appropriately
Causes spasms or constriction

The treatment for EoE

Elimination diet (remove wheat, eggs, milk, soy, shellfish and seafood, peanuts and tree nuts)
Topical or systemic steroids

The potential increased prevalence of EoE in children with celiac disease

2015 paper found prevalence of 10.7% (much higher than general population)
Other research articles argue no increased prevalence of EoE in CD

The case study of a 30-year-old woman with celiac disease and elevated eosinophils

Presented with abdominal pain and distension, vomiting and frequent bowel movement
Treated with IV hydrocortisone, but developed steroid induced psychosis

Nadine’s insight on the best specialty clinics for EoE in the US

University of Colorado (Denver School of Medicine)
Pennsylvania

Dr. Glenn Furuta’s insight on the difficulty of diagnosing EoE

Relatively new disease, tendency to diagnose based on pathology report alone
Elevated eosinophils also found in GERD, inflammatory bowel disease and celiac disease

Special considerations for pediatric patients with EoE