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Hepatitis B Vaccine and Celiac Disease EP060

We get vaccinated to protect ourselves, to gain an immunity to a particular disease. But in the case of hepatitis B, celiac patients may come to find out that we are NOT immune—despite having done the right thing in getting a hepatitis B vaccination.

Today, the Gluten Free RN is walking us through the latest research around vaccination and celiac disease. She explores the fact that celiac patients are more likely to be non-responsive to HBV than the general population, explaining the fundamentals of hepatitis B and the two main theories as to why the vaccine doesn’t work for some celiac patients.

Nadine shares her take on immunizations, explaining why she is a proponent of an alternate vaccination schedule for infants who may be immunocompromised. Listen in and learn how to determine whether you are truly immune to hepatitis B and protect yourself from potentially life-threatening disease!

What’s Discussed: 

The basics of hepatitis B (HBV)

  • Viral infection that attacks liver
  • Transmitted through blood, body fluids

The prevalence of hepatitis B

  • 257M people infected
  • 887K deaths in 2015

The 2013 Italian study around celiac disease and the hepatitis B vaccine

  • Number of non-responders to vaccine higher in CD patients
  • May be genetic OR caused by gluten intake during vaccination

Nadine’s experience with vaccination as a child

  • Contracted mumps despite MMR

Nadine’s take on vaccination

  • Advocates for immunization to prevent disease
  • Giving babies multiple vaccines at once may not be best

The conclusion of a 2017 Italian study

  • Administer booster shots of hepatitis B vaccine as needed
  • Evaluate response to vaccine in newly diagnosed celiac patients
  • Revaccinate one year after adoption of gluten-free diet

The value of a hepatitis B titer

  • Confirms whether really immune
  • If not, test for celiac disease

Resources:

‘Hepatitis B Vaccine in Celiac Disease: Yesterday, Today and Tomorrow in the World Journal of Gastroenterology

‘Vaccinations in Celiac Disease’ in the Journal of Pediatric Gastroenterology and Nutrition

‘Immune Response to Vaccines in Children with Celiac Disease’ in the World Journal of Gastroenterology

‘Immune Response to Hepatitis B Vaccine in Patients with Celiac Disease: A Systematic Review and Met-Analysis’ in Human Vaccines and Immunotherapeutics

‘Early Vaccinations are Not Risk Factors for Celiac Disease’ in Pediatrics

‘Gluten Intake Interferes with the Humoral Immune Response to Recombinant Hepatitis B Vaccine in Patients with Celiac Disease’ in Pediatrics

‘Effect of Pentavac and Measles-Mumps-Rubella (MMR) Vaccination on the Intestine’ in Gut

‘Normal of Defective Immune Response to Hepatitis B Vaccine in Patients with Diabetes and Celiac Disease’ in Human Vaccines and Immunotherapeutics

Connect with Nadine:

Instagram

Facebook

Contact via Email

‘Your Skin on Gluten’ on YouTube

Melodies of the Danube Gluten-Free Cruise with Nadine

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

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Celiac Disease and Your Spleen EP029

Did you know that the spleen plays a leading role in a properly functioning immune system? As the largest organ in your lymphatic system, the spleen spends its time fighting infection and keeping you healthy. Unfortunately, research points to a connection between disorders of the spleen and celiac disease. And if your immune system is already compromised because of gluten damage to your intestines, a spleen issue leaves you at heightened risk for a variety of infections and autoimmune diseases.

Today the Gluten Free RN shares her personal connection to genetic spherocytosis and how spleen damage affected her family. She also covers several studies that document the correlation between spleen issues and celiac disease. Listen in to understand how your spleen functions, the symptoms of spleen disorder, and the autoimmune diseases you may develop if your spleen is damaged or removed.

What’s Discussed:

How your spleen works to keep you healthy

  • Filters used/damaged red blood cells
  • Harvests iron to recycle
  • Produces antibodies, white blood cells
  • Fights infection
  • Vital to immune system

Conditions you may acquire if spleen is damaged (increased risk)

  • Pneumonia
  • UTI
  • Overwhelming sepsis

Instances in which spleen may be enlarged

  • Mononucleosis
  • Some bacterial infections, metabolic disorders
  • Liver diseases
  • Some blood cancers, lymphoma
  • Blood clots in veins of liver, spleen

Symptoms of spleen issues

  • Pain in upper left quadrant
  • Fatigue
  • Anemia
  • Bruise easily
  • Bloated

The correlation between genetic spherocytosis and celiac disease

  • As high as 88% in some studies

How the ratio of spleen diameter to RDW can indicate celiac disease

  • Two-thirds of celiac patients in study had elevated red blood cell distribution width
  • Small spleen in 80% of celiac patients
  • Spleen diameter to RDW ratio under 6 had 88.5% specificity in predicting celiac disease

Why patients with hyposplenism should get tested for celiac disease

  • 25-75% of celiac patients have hyposplenism
  • Look for red blood cell abnormality
  • HLA-DQ2 and HLA-DQ8 genes indicate predisposition for celiac disease
  • Antibody test available from EnteroLab or Cyrex Laboratories
  • Ask for total IgA, IgG

Other autoimmune diseases patients with hyposplenism may develop (increased risk)

  • Type 1 diabetes
  • Lupus
  • Sjögren’s syndrome
  • Vitiligo
  • Raynaud’s
  • Autoimmune thyroiditis
  • ALS, MS, any demyelination of nervous system
  • Idiopathic thrombocytopenia
  • Autoimmune hepatitis

Nadine’s recommendations around nutrition

  • Local, organic
  • Nutrient dense
  • Gluten-free, Paleo

The link between hyposplenism and autoimmune manifestations of celiac disease

  • Autoimmune disorders may cause splenic hypofunction or vice versa
  • Study hypothesizes that higher risk for splenic function in celiac patients may be related to celiac disease rather than autoimmunity
  • Prevalence of celiac disease-associated hyposplenism increased from 19% in uncomplicated patients to 59% in those with autoimmune disorders

Why celiac patients may not benefit from iron supplements, infusions

  • Damaged intestines cannot absorb iron
  • Damaged spleen destroys healthy red blood cells

Resources:

“Ratio of Spleen Diameter to Red Blood Cell Distributions Width” in Medicine (Baltimore)

EnteroLab

Cyrex Laboratories

“Is it Worth Investigating Splenic Function in Patients with Celiac Disease?” in the World Journal of Gastroenterology

“Hyposplenism in Gastrointestinal Disease” in Gut BMJ

“Hyposplenism, Adult Coeliac Disease, and Autoimmunity” in Gut BMJ

“Splenic Volume Differentiates Complicated and Non-Complicated Celiac Disease” in UEG Journal

Connect with Nadine: 

Instagram

Facebook

Contact via Email

‘Your Skin on Gluten’ on YouTube

Melodies of the Danube Gluten-Free Cruise with Nadine

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

 

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Neurological Disorders Associated with Celiac Disease and Gluten Sensitivity EP012


Nadine covers the neurological symptoms associated with celiac disease and non-celiac gluten sensitivity. Celiac disease is primarily a neurological disorder, but the neurological symptoms are often misdiagnosed.

 Nadine shares her own story as well as client anecdotes regarding the neurological issues faced by celiac patients and those with non-celiac gluten sensitivity. She outlines the common symptoms and discusses how to either slow their progression or eliminate them entirely.

Nadine explains the way gluten affects your neurological system and how a Paleo lifestyle can help you heal. Listen and understand how to get your brain back!

 What’s Discussed:

How an immobile patient misdiagnosed with MS was able to walk again

  • Inspired by Dr. Terry Wahls book, The Wahls Protocol, she adopted a Paleo diet
  • Food can be medicine or poison

Misdiagnoses given to people who actually suffered from gluten ataxia

  • Parkinson’s
  • ALS
  • MS
  • Psychosomatic disorder

Why experts advocate for including an AGA in celiac testing

  • It provides a biomarker for non-celiac gluten sensitivity

Why the neurological component of celiac disease and non-celiac gluten sensitivity is so significant

  • The entire enteric nervous system is located in the bowels
  • Constipation and diarrhea occur when peristalsis is paralyzed due to gluten

The neurological symptoms of celiac disease and non-celiac gluten sensitivity

Why patients diagnosed with Alzheimer’s or dementia could be restored by a Paleo diet

  • An autopsy is the only way to definitively diagnose Alzheimer’s
  • Many patients have improved significantly after removing gluten from their diets

The components of a Paleo diet

  • Meats and fish
  • Nuts and seeds
  • Fruits and vegetables

How a Paleo lifestyle cleared Nadine’s neurological issues

  • Her balance issues went away
  • She no longer suffered frequent falls

The standard nutritional panels for a celiac patient

How glyphosates can cause leaky gut even in the absence of celiac disease or non-celiac gluten sensitivity

The health benefits Nadine has witnessed in patients who adopt a Paleo diet

  • No longer take prescription medication
  • Normal blood pressure
  • Desirable cholesterol level
  • Absorb nutrients appropriately
  • Body heals

 Resources Mentioned: 

 The Wahls Protocol by Dr. Terry Wahls

Discovery Health: Celiac Disease

Connect with Nadine: 

Instagram

Facebook

Contact via Email

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

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Regain and Maintain Your Health with a Paleo Diet EP009

This episode of the ‘Gluten Free RN’ podcast outlines the benefits of adopting a Paleo diet in order to regain and then maintain your health. Patients with celiac disease or gluten intolerance can get better, faster by choosing the Paleo option.

 Nadine shares how changing her eating habits had an incredibly positive impact on her health as she went from feeling better on a gluten-free diet to feeling fantastic on her own variation of a Paleo diet.

 Nadine gets specific about the foods you can and cannot eat and the incredible health benefits of going Paleo. Listen in and learn how to get back the health you deserve by focusing on good food!

 What’s Discussed: 

The foods to avoid on a Paleo diet

The foods you can eat on a Paleo diet

Nadine’s story

The concept of food as medicine

  • All disease starts in the gut

Where to locate organic fruits and vegetables and meat with no antibiotics/no hormones

The health benefits of a Paleo diet

  • Clears up lingering gluten issues
  • Helps achieve sustainable weight loss
  • Affords clearer, smoother skin
  • Improves the immune system
  • Allows for better sleep

The importance of sleep hygiene

  • Your body heals while you sleep
  • Eight to ten hours is optimal

Why fat is essential in absorbing nutrients

  • Vitamins A, D, E & K are fat soluble

The best sources of fat for nutrient absorption

  • Avocadoes
  • Grass fed meats
  • Olive oil or coconut oil
  • Nuts
  • Nut butters
  • Fish oil
  • Eggs

 Resources Mentioned: 

Paleo Magazine

The Paleo Solution: The Original Human Diet by Robb Wolf

Practical Paleo by Diane Sanfilippo

The Paleo Approach: Reverse Autoimmune Disease and Heal Your Body by Sarah Ballantyne

Midway Farms http://www.midwayfarmsoregon.com/

Connect with Nadine: 

Instagram

Facebook

Contact via Email

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

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Intestinal Health and Antibiotic Resistant Threats EP008


This time on the ‘Gluten Free RN’ podcast, Nadine explores the connection between gluten intolerance and antibiotic-resistant threats. Because damaged intestines compromise the immune system, undiagnosed celiac patients are more likely to develop infections that necessitate antibiotics.

 Nadine summarizes the 2013 CDC report, Antibiotic Resistance Threats in the United States, explaining the three microorganisms identified in the report with a Threat Level of Urgent. Listen and learn how to protect yourself and your family from the public health threat posed by these bacteria!

 What’s Discussed: 

The prevalence of undiagnosed celiac disease and gluten intolerance

  • 30-50% of the population carry the HLA-DQ2 and/or DQ8 genes

The importance of healthy intestinal tissue

  • 70-90% of the immune system is in your intestines

The soldier analogy

  • Healthy villi are like rested soldiers with loaded weapons on a clear day who can easily take out antigens that don’t belong
  • Damaged villi are like soldiers on a bender with inadequate weaponry, operating in smoke and fire – they either don’t work at all or fire randomly at antigens

The need for a more judicious approach to prescribing antibiotics

  • Overuse of antibiotics wipes out good microbiome along with bad

How to rebuild microbiome

  • Kombucha
  • High-quality probiotics
  • Fermented foods
  • Apple cider vinegar

The need for IgA and IgG testing to complement a celiac panel

The public health threat posed by antibiotic-resistant bacteria

  • The 2013 CDC report details 2 million illnesses and 23,000 deaths yearly

The connection between damaged intestines and a higher risk of bacterial infection requiring antibiotics

The three microorganisms with a Threat Level of Urgent

  • Clostridium difficile (causes profuse diarrhea, 14,000 deaths/year)
  • Carbapenem-resistant Enterobacteriaceae (50% fatal, 600 deaths/year)
  • Neisseria gonorrhoeae

The causes of inflammation in your intestines

  • Gluten
  • Dairy
  • Sugar

Why Nadine has concerns about the potential pandemic and huge loss of life presented by large numbers of undiagnosed celiac patients who are susceptible to bacterial infections

 Resources Mentioned: 

 CDC Report: Antibiotic Resistance Threats in the United States, 2013

Enterolab Website

Cyrex Laboratories Website

PubMed

Connect with Nadine: 

Instagram

Facebook

Contact via Email

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

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Intro to Celiac Disease and Gluten Intolerance EP004


This episode of ‘Gluten Free RN’ covers the basics of celiac disease and gluten intolerance – what those terms mean and what they might mean for you. Nadine explains which genes suggest a predisposition to gluten intolerance and what circumstances lead to a diagnosis of celiac disease proper.

 Nadine talks you through what happens in your digestive tract that leads to gluten proteins attacking your organs and preventing your body from absorbing the nutrients it needs. She also outlines the foods and products you need to avoid to achieve ‘gluten-zero,’ as well as the foods you can enjoy as part of a gluten-free diet.

 Listen in and learn where gluten is hiding and how to modify your diet to reverse the adverse effects of gluten!

What’s Discussed: 

  • The definition of celiac disease and its chronic nature
    • 30-50% of the population carries the genes
  • How a trigger event (i.e.: a cold, pregnancy, stress, an injury) initiates the autoimmune disorder
  • Options for getting tested for the genetic predisposition
  • The closed system of the digestive tractand how food is processed
    • While some food is used for energy, much just passes through
  • Villous atrophy and the four stages of tissue damage
    • Marsh 1: microvilli destroyed; body cannot break down sugar and milk
    • Marsh 2/3: villi themselves fold over or atrophy; tight junctures between villi (that keep things your body can’t utilize in the GI tract and out of your bloodstream) open up
    • Marsh 4: villi gone and only red, inflamed tissue remains; ‘leaky gut’
  • The effects of increased permeability of the intestinal wall
    • Damaged immune system
    • Rather than passing through the GI tract, gluten proteins get into bloodstream and wreak havoc on organs
    • Body can’t absorb nutrients out of food
  • The importance of healthy intestinal tissue
    • 70-90% of the immune system is in your intestines
  • The soldier analogy
    • Healthy villi are like rested soldiers with loaded weapons on a clear day who can easily take out antigens that don’t belong
    • Damaged villi are like soldiers on a bender with inadequate weaponry, operating in smoke and fire – they either don’t work at all or fire randomly at antigens
  • The long road to recovering from villous atrophy
    • It takes 6 months to a year to reverse the damage
  • Grains to avoid that contain gluten
    • Wheat
    • Barley
    • Rye
    • Oats (due to cross-contamination)
  • Places where gluten may be hiding
  • Gluten-free foods
    • Fresh fruits and vegetables
    • Plain meats and fish (not breaded or beer battered)
    • Beans/legumes
    • Tree nuts
    • Rice, corn and potatoes
    • Quinoa and teff
    • Dairy
  • What a gluten-free rating means
    • The Gluten Intolerance Group (GIG) certifies products that contain less than ten parts per million

Resources Mentioned: 

Gluten: Zero Global by Rodney Ford

 Enterolab Website

 Glutenpro Celiac Test

 Country Life Vitamins

 Kite Hill Foods

Connect with Nadine: 

Instagram

Facebook

Contact via Email

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

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Food is Medicine – EP001

In the premier episode of ‘Gluten Free RN’ Nadine tells us a bit about her journey in regaining her health and why it’s so important to understand that food is medicine to our bodies. If we think about food as medicine, we will make better food choices which will lead to much better health in both the short and long term.

Nadine also discusses the increasing rate of Celiac disease diagnosis and some factors that may be influencing this.

Listen in to learn why it’s so important to make good food choices and how making the right ones will help you maintain or even regain your health!

What’s Discussed:

  • Nadine’s background
  • Nurse for 25 years, 10 years as the Gluten Free RN
  • At the time, Nadine didn’t know that gluten intolerance and Celiac disease were often big factors in her patients’ health problems
  • Why Nadine considers herself to be a “Connectologist”
  • Nadine connects some dots that may not have been previously connected
  • Why Gluten sensitivity and/or Celiac disease is often common denominator in health problems
  • Why food is medicine and how that affects our health
  • Nadine’s journey back from bad health
  • Learned she had Celiac disease at the age of 40
  • Your GI Tract and immune system
  • 70-90 % of your immune system is in your GI tract
  • As humans, we do not have do not have enzymes to break down gluten proteins
  • Why you may be predisposed to Celiac disease
  • 30-50% of our population carries the genes that predispose us to Celiac disease
  • The increasing rate of Celiac disease diagnosis
  • The importance of having a plan for remaining or getting healthy into your 60’s, 70’s, 80’s and 90’s
  • It’s easier to maintain your health than to regain it
  • Nadine’s diet recommendations
  • Common problems of a bad diet
  • Topics that will be discussed in future episodes!

Resources Mentioned: 

Seeds of Deception” by Jeffery Smith

Connect with Nadine: 

Instagram

Facebook

Contact via Email

Books by Nadine:

Dough Nation: A Nurse’s Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism